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Chemical probe design
& Bioconjugation chemistry
Transcriptional regulation
Modulation of RNA splicing
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Chemical probe design
107. Biocatalytic Synthesis of Ribonucleoside Analogues Using Nucleoside Transglycosylase-2
October 1, 2024
104. A framework for the biophysical screening of antibody mutations targeting solvent-accessible hydrophobic and electrostatic patches for enhanced viscosity profiles
May 23, 2024
102. Innovative, combinatorial and high-throughput approaches to degrader synthesis
April 10, 2024
98. Glutathione Mediates Control of Dual Differential Bio-orthogonal Labelling of Biomolecules
October 31, 2023
97. Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome
January 17, 2023
96. Fluorous-Directed Assembly of DNA Origami Nanostructures
December 20, 2022
95. Surface Passivation with a Perfluoroalkane Brush Improves the Precision of Single-Molecule Measurements
October 28, 2022
94. Oligonucleotide-Recognizing Topoisomerase Inhibitors (OTIs): Precision Gene Editors for Neurodegenerative Diseases?
September 29, 2022
93. Biophysical characterisation of the Bcl-x pre-mRNA and binding specificity of the ellipticine derivative GQC-05: Implication for alternative splicing regulation
August 17, 2022
92. Biosynthesis of Aurodox, a Type III Secretion System Inhibitor from Streptomyces goldiniensis
July 18, 2022
91. A Chemo- and Regioselective Tandem [3 + 2]Heteroannulation Strategy for Carbazole Synthesis: Combining Two Mechanistically Distinct Bond-Forming Processes
March 18, 2022
90. Direct, Late-Stage Mono-N-arylation of Pentamidine: Method Development, Mechanistic Insight, and Expedient Access to Novel Antiparastitics against Diamidine-Resistant Parasites
August 6, 2021
89. A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications
May 27, 2021
87. Contra-thermodynamic E → Z isomerization of cinnamamides via selective energy transfer catalysis
December 18, 2020
88. Glasgow Early Treatment Arm Favirpiravir (GETAFIX) for adults with early stage COVID-19: A structured summary of a study protocol for a randomised controlled trial
November 19, 2020
85. Identification of 2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)amino)-N-phenylpropanamides as a novel class of potent DprE1 inhibitors
June 15, 2020
86. Biocatalytic Alkylation Cascades: Recent Advances and Future Opportunities for Late-Stage Functionalization
May 27, 2020
84. Two-dimensional infrared spectroscopy: an emerging analytical tool?
February 10, 2020
62. A Tandem Enzymatic sp2-C-Methylation Process: Coupling in Situ S-Adenosyl-l-Methionine Formation with Methyl Transfer (ChemBioChem 11/2017)
May 15, 2017
64. Strategy for Conditional Orthogonal Sequential CuAAC Reactions Using a Protected Aromatic Ynamine
April 28, 2017
63. Ultrafast 2D-IR and optical Kerr effect spectroscopy reveal the impact of duplex melting on the structural dynamics of DNA
April 6, 2017
61. Reversible DNA micro-patterning using the fluorous effect
February 23, 2017
60. Determining the Origin of Rate-Independent Chemoselectivity in CuAAC Reactions: An Alkyne-Specific Shift in Rate-Determining Step
February 16, 2017
59. Transition-Metal-Free Amine Oxidation: A Chemoselective Strategy for the Late-Stage Formation of Lactams
February 8, 2017
42. An oligofluorene truxene based distributed feedback laser for biosensing applications
April 15, 2014
34. Directed Assembly of DNA-Functionalized Gold Nanoparticles Using Pyrrole–Imidazole Polyamides
May 7, 2012
33. Photo-induced growth of DNA-capped silver nanoparticles
March 2, 2012
30. DNA-Templated Photonic Arrays and Assemblies: Design Principles and Future Opportunities
June 10, 2011
29. Site-Specific Assembly of DNA-Based Photonic Wires by Using Programmable Polyamides
February 25, 2011
27. Cu-Catalyzed N-Alkynylation of Imidazoles, Benzimidazoles, Indazoles, and Pyrazoles Using PEG as Solvent Medium
January 4, 2010
26. Highly Efficient Synthesis of DNA-Binding Hairpin Polyamides via the Use of a New Triphosgene Coupling Strategy
August 11, 2009
4. New labelling strategies for the sensitive detection of nucleic acids
January 1, 2005