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62. A Tandem Enzymatic sp2-C-Methylation Process: Coupling in Situ S-Adenosyl-l-Methionine Formation with Methyl Transfer (ChemBioChem 11/2017)

62. A Tandem Enzymatic sp2-C-Methylation Process: Coupling in Situ S-Adenosyl-l-Methionine Formation with Methyl Transfer (ChemBioChem 11/2017)
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Conference

Abstract

The inside back cover picture shows a one-pot tandem reaction involving in situ enzymatic synthesis of S-adenosylmethionine by using SalL, followed by C−C bond formation by using the C-methyltransferase NovO. This system is compatible with both methionine and methionine analogues as the alkyl donor. More information can be found in the communication by L. D. Humphreys, G. A. Burley et al. on page 992 in Issue 11, 2017 (DOI: 10.1002/cbic.201700115).

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Link to publication

https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cbic.201700244