Bioconjugation chemistry

109. Assessing the Manufacturability and Critical Quality Attribute Profiles of Anti-IL-8 Immunoglobulin G Mutant Variants

107. Reactivity Profiling for High-Yielding Ynamine-Tagged Oligonucleotide Click Chemistry Bioconjugations

105. A First Insight into the Developability of an Immunoglobulin G3: A Combined Computational and Experimental Approach

104. A framework for the biophysical screening of antibody mutations targeting solvent-accessible hydrophobic and electrostatic patches for enhanced viscosity profiles

103. Mechanistic Basis of the Cu(OAc)2 Catalyzed Azide-Ynamine (3 + 2) Cycloaddition Reaction

102. Innovative, combinatorial and high-throughput approaches to degrader synthesis

99. Antibody-Proteolysis Targeting Chimera Conjugate Enables Selective Degradation of Receptor-Interacting Serine/Threonine-Protein Kinase 2 in HER2+ Cell Lines

98. Glutathione Mediates Control of Dual Differential Bio-orthogonal Labelling of Biomolecules

96. Fluorous-Directed Assembly of DNA Origami Nanostructures

83. Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase Inhibitors: Expeditious Reconstruction of Suboptimal Hits into a Series with Potent in Vivo Activity

77. Sequence-Selective Minor Groove Recognition of a DNA Duplex Containing Synthetic Genetic Components

74. Organic Semiconductor Laser Platform for the Detection of DNA by AgNP Plasmonic Enhancement

70. Effect of oligomer length on vibrational coupling and energy relaxation in double-stranded DNA

66. Modular, Step-Efficient Palladium-Catalyzed Cross-Coupling Strategy To Access C6-Heteroaryl 2-Aminopurine Ribonucleosides

65. Synthetic biological approaches for RNA labelling and imaging: design principles and future opportunities

49. SERS enhancement of silver nanoparticles prepared by a template-directed triazole ligand strategy

46. Defining the Structural Parameters of Triazole Ligands in the Templated Synthesis of Silver Nanoparticles

44. Malaria Protein Kinase CK2 (PfCK2) Shows Novel Mechanisms of Regulation

35. Orthogonal, metal-free surface modification by strain-promoted azide–alkyne and nitrile oxide–alkene/alkyne cycloadditions

34. Directed Assembly of DNA-Functionalized Gold Nanoparticles Using Pyrrole–Imidazole Polyamides

32. Triazoles from N-Alkynylheterocycles and Their Coordination to Iridium

27. Cu-Catalyzed N-Alkynylation of Imidazoles, Benzimidazoles, Indazoles, and Pyrazoles Using PEG as Solvent Medium

26. Highly Efficient Synthesis of DNA-Binding Hairpin Polyamides via the Use of a New Triphosgene Coupling Strategy

24. Chain-like assembly of gold nanoparticles on artificial DNA templates via ‘click chemistry’

23. Pronounced Effect of DNA Hybridization on Click Reaction Efficiency

22. Synthesis of Highly Modified DNA by a Combination of PCR with Alkyne-Bearing Triphosphates and Click Chemistry

21. Transfer Printing of DNA by “Click” Chemistry

19. Formation of Bimetallic Ag/Au-Nanowires by Metallization of Artificial DNA-Duplexes

18. Click chemistry as a reliable method for the high-density functionalisation of alkyne-modified oligodeoxyribonucleotides